Toxtree (Ideaconsult) is a flexible and user-friendly open-source application that places chemicals into categories and predicts various kinds of toxic effect by applying decision tree approaches.

The following decision trees are currently implemented: the Cramer classification scheme, Verhaar scheme for aquatic modes of action, rulebases for skin and eye irritation and corrosion, Benigni-Bossa rulebase for mutagenicity and carcinogenicity, structural alerts for protein and DNA binding, Kroes TTC decision tree, CYP450-mediated drug metabolism, START rulebase for persistence / biodegradation potential.